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IL-18是一种Th1细胞因子,它能高水平诱生IFN-,增强NK细胞活性,显著增强TH1型免疫反应,调节各种细胞因子的生成,具有明显的抗肿瘤功能。本文主要就IL-18的来源、生物学功能及抗脑肿瘤研究进展作一介绍。
IL-18 is a Th1 cytokine that induces IFN- at high levels, enhances NK cell activity, significantly enhances TH1-type immune responses, regulates the production of various cytokines and has significant anti-tumor effects. This article mainly introduces the origin, biological function and research progress of anti-brain tumor of IL-18.