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为了阐明肝癌与某些危险因素如乙型肝炎病毒、日本血吸虫病和酒精的关系,作者于1977年4月至1979年8月进行了病例-对照研究。62例肝癌病例来自山梨县血吸虫病流行区的7个医院。按性别、年龄和就诊医院配对选择同等数目的肝癌和对照病例。肝癌病例中,36例(58.0%)经肝活检、17例(27.5%)甲胎蛋白阳性(其中13例兼有实验室检查阳性结果)、9例(14.5%)经实验室检查(包括腹腔镜、血管造影摄片、闪烁图或超声图)获阳性结果而确诊。对照病例中均肯
To elucidate the relationship between hepatocellular carcinoma and certain risk factors such as hepatitis B virus, schistosomiasis japonica and alcohol, a case-control study was conducted from April 1977 to August 1979. Sixty-two HCC cases were from seven hospitals in the endemic area of schistosomiasis in Yamanashi Prefecture. Select the same number of HCCs and control cases by sex, age and paired hospital visit. Among liver cancer cases, 36 (58.0%) were biopsied by liver biopsy, 17 (27.5%) were positive for alpha-fetoprotein (13 were positive for laboratory test) and 9 were (14.5% Mirror, angiogram, scintigraphy, or ultrasound) was confirmed positive. Control cases are willing to