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辐射对女性生殖功能的影响一直是辐射效应研究中的一个热点。长崎ABCC/RERF的成人健康研究(AHS)人群中,有1507名妇女在原爆时年龄小于40岁,1955年时尚未绝经,且具有DS86剂量。到分析时止,这些妇女中,有1006名妇女已绝经,其余501人中,135人尚未绝经,366人因各种原因终止检查。资料处理采用了发病率分析方法,根据绝经年龄、出生队列(即原爆时年龄)、DS86总的Kerma剂量(Gy)。将资料归纳为发生绝经的三维列联人年表,并引入Possion近似法计算相对危险。分析的模型为:λ_i(d)=λ_i(0)X RR(d)
The impact of radiation on female reproductive function has been a hot spot in the study of radiation effects. In the Nagasaki ABCC / RERF Adult Health Study (AHS) population, 1507 women were less than 40 years of age at the time of the primary blast and had not yet been menopause in 1955 and had a dose of DS86. At the time of analysis, out of these women, 1006 were postmenopausal and out of the remaining 501, 135 were not yet menopause and 366 were terminated for various reasons. Data processing used a morbidity analysis based on the age of the menopause, the birth cohort (ie, the age of the primary blast), and the total Kerma dose (Gy) for the DS86. The data are summarized as the menopause of the three-dimensional United Nations chronology, and the introduction of Possion approximation method to calculate the relative risk. The analytical model is: λ_i (d) = λ_i (0) X RR (d)