目的:探讨甲状舌管乳头状癌病例的诊断治疗方法。方法:2例患者术前接受常规体检、B超、细针穿刺检查,手术均包括颈前肿块及舌骨中部的切除(Sistrunk operation),一侧甲状腺肿块切除或腺叶切除。一例患者由于发现明显右颈肿大淋巴结,故同时实施了功能性颈清扫术。术后标本行常规病理检查。结果:2例患者标本符合甲状舌管乳头状癌诊断,并正在密切随访中。结论:甲状舌管癌为罕见病种,已有公认的诊断标准,Sistrunk手术仍为一种适当的外科治疗方法。 Objective: To investigate the diagnosis and treatment of thyroglossal papillary carcinoma. Methods: Two patients underwent preoperative routine physical examinations, B-ultrasound and fine needle aspiration. Surgical procedures included Sistrunk operation of the anterior cervical mass and hyoid bone, and thyroidectomy or lobectomy on one side. One patient had a functional neck dissection at the same time because of a clear right neck and enlarged lymph node. Postoperative specimens routine examination. Results: Two patients were diagnosed with thyroglossal papillary carcinoma and were under close follow-up. CONCLUSIONS: Thyroid cancer is a rare disease that has been recognized as a diagnostic criteria and Sistrunk surgery remains an appropriate surgical treatment.