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目的:探讨血、尿淀粉酶在诊断急性有机磷农药中毒(AOPP)患者胰腺损伤时的临床意义。方法:128例患者按入院时中毒的程度分为轻度组38例、中度组42例、重度组48例,比较正常对照组与各中毒组之间血、尿淀粉酶的变化;根据MODS诊断标准,分为MODS组36例和非MODS组92例,比较对照组与MODS组和非MODS组血、尿淀粉酶的变化,以及MODS组和非MODS组血、尿淀粉酶的变化。结果:中、重度中毒组血、尿淀粉酶较对照组和轻度中毒组差异有统计学意义(P<0.01),MODS、非MODS组与对照组比较差异有统计学意义(P<0.01),MODS组与非MODS组比较差异有统计学意义(P<0.01)。结论:AOPP患者血、尿淀粉酶愈高,病情愈重,与预后密切相关。
Objective: To investigate the clinical significance of blood and urine amylase in the diagnosis of pancreatic injury in patients with acute organophosphorus pesticide poisoning (AOPP). Methods: According to the degree of poisoning, 128 patients were divided into mild group (n = 42), moderate group (n = 42) and severe group (n = 48). The changes of blood and urine amylase in normal control group and each poisoning group were compared. The diagnostic criteria were divided into MODS group (36 cases) and non-MODS group (92 cases). The changes of blood and urine amylase in the control group, MODS group and non-MODS group were compared with those in MODS group and non-MODS group. Results: The levels of blood and urine amylase in the moderate and severe poisoning groups were significantly different from those in the control group and the mild poisoning group (P <0.01). There was significant difference between the MODS group and the non-MODS group and the control group (P <0.01) , There was significant difference between MODS group and non-MODS group (P <0.01). Conclusion: AOPP patients with higher blood and urine amylase, the more serious the disease, and the prognosis are closely related.