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目的探讨心外膜脂肪组织(EAT)与颈总动脉内中膜厚度(CIMT)、冠心病的相关性,进一步分析EAT预测冠心病的意义。方法入选确诊冠心病需行冠脉造影住院患者160例(其中非冠心病86例,冠心病74例),入院后10 d内彩超检测EAT厚度、CIMT厚度,分析EAT厚度与CIMT厚度、冠心病的相关性。结果相关性分析显示,EAT厚度与CIMT有较好的相关性(r=0.79,P<0.001);冠心病组EAT、CIMT较非冠心病组明显高〔(8.65±1.45)vs(6.30±1.53)mm;(1.17±0.21)vs(0.83±0.19)mm;均P<0.01)〕;CIMT≥0.92 mm预测冠心病的敏感度、特异度、Youden指数分别为0.81、0.78、0.59,EAT≥7.24 mm预测冠心病的敏感度、特异度分别为0.84、0.80、0.64。结论超声检测EAT和CIMT可作为冠心病的预测指标。
Objective To investigate the relationship between epicardial fat tissue (EAT) and carotid artery intima - media thickness (CIMT) and coronary heart disease (CAD), and further analyze the significance of EAT in predicting coronary heart disease. Methods One hundred and sixty inpatients undergoing coronary angiography (including 86 non-coronary heart disease and 74 coronary heart disease) undergoing coronary angiography were enrolled in this study. EAT and CIMT thickness were measured by color Doppler ultrasound within 10 days after admission. EAT thickness, CIMT thickness, coronary heart disease Relevance. Results Correlation analysis showed that there was a good correlation between EAT thickness and CIMT (r = 0.79, P <0.001). EAT and CIMT in patients with coronary heart disease were significantly higher than those without coronary heart disease (8.65 ± 1.45 vs 6.30 ± 1.53 ); (1.17 ± 0.21) vs (0.83 ± 0.19) mm; all P <0.01); The sensitivity, specificity and Youden index of coronary heart disease predicted by CIMT≥0.92 mm were 0.81,0.78,0.59 and EAT≥7.24 mm prediction of coronary heart disease sensitivity, specificity were 0.84,0.80,0.64. Conclusion Ultrasound detection of EAT and CIMT can be used as a predictor of coronary heart disease.