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近40多年来食管静脉曲张破裂出血的死亡率和发病率几乎无甚改变,最近几年报告的资料均表明尽管冶疗手段众多,包括外科手术、填塞出血曲张静脉及电凝等,但无一种卓有成效的方法.鉴于此,药物治疗仍是最基本的措施.血管加压素 19世纪末,从垂体后叶提出血管加压素已知对心血管系统有明显的抑制作用.随后 Clark 证明血管加压素可增加肝动脉血压和降低门脉压力。相继许多研究报告应用血管加压素来控制上消化道急性大出血.过去25年中有4组材料报告血管加压素控制出血成功率为40%(Conn)～100%(sherlock).但没设对照组,难以令人信
Nearly 40 years of esophageal variceal bleeding mortality and morbidity almost unchanged, the data reported in recent years have shown that despite the many means of treatment, including surgery, bleeding varicose veins and coagulation, etc., but none In this regard, drug treatment is still the most basic measure Vasopressin Vasopressin from the posterior pituitary gland was known to have a marked inhibitory effect on the cardiovascular system at the end of the nineteenth century, and Clark subsequently demonstrated that vasopressin Hormone can increase hepatic arterial pressure and reduce portal pressure. A number of studies have reported the use of vasopressin to control acute upper gastrointestinal bleeding, with a success rate of 40% (Conn) to 100% (sherlock) reported in 4 of the last 25 years in vasopressin control but no control Group, unbelievable