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目的：为了解肝癌与α－Ｌ－岩藻糖苷酸的关系。方法：采用改良微量比色法对１２２例病人及１００例正常体检者的血α－Ｌ－岩藻糖苷酸酶（ＡＦＵ）进行检测。结果：１００例正常对照ＡＦＵｘ＝２６５．８ｍｍｏｌ．Ｌ－１．ｈ－１；ｓ＝１１８．６ｍｍｏｌ．Ｌ－１．ｈ－１；原发性肝癌（ＰＨＣ）４３例，ｘ＝６２９．５ｍｍｏｌ．Ｌ－１．ｈ－１，ｓ＝２１１．７ｍｍｏｌ．Ｌ－１．ｈ－１；肝硬化（ＬＣ）５２例，ｘ＝３３２．９ｍｍｏＬ．Ｌ－１．ｈ－１，ｓ＝２２６ｍｍｏｌ．Ｌ－１．ｈ－１；消化道癌２７例，ｘ＝３１３．２ｍｍｏｌ．Ｌ－１．ｈ－１，ｓ＝１５４ｍｍｏｌ．Ｌ－１．ｈ－１。结论：ＰＨＣ与正常对照组差别有极显著意义（Ｐ＜０．００１），且ＰＨＣ明显高于ＬＣ组及消化道癌组（Ｐ＜０．０１），特别对甲胎蛋白（ＡＦＰ）阳性的病人有重要的临床诊断价值。
Objective: To understand the relationship between liver cancer and α-L-fucoidate. Methods: The serum α-L-fucosylase (AFU) in 122 patients and 100 normal subjects were detected by modified microchromatography. Results: 100 normal controls AFUx = 265.8 mmol. L-1. H-1;s=118.6 mmol. L-1. H-1; primary liver cancer (PHC) in 43 cases, x = 629.5 mmol. L-1. H-1, s=211.7 mmol. L-1. H-1; Liver cirrhosis (LC) in 52 cases, x = 332.9 mmoL. L-1. H-1,s=226mmol. L-1. H-1; gastrointestinal cancer in 27 cases, x = 313.2 mmol. L-1. H-1,s=154 mmol. L-1. H-1. Conclusion: The difference between PHC and normal control group is extremely significant (P<0.001), and PHC is significantly higher than that of LC group and gastrointestinal cancer group (P<0.01), especially for alpha-fetoprotein (AFP) positive Patients have important clinical diagnostic value.