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P<0.01结果如表2所示,生精固本丸在2.5g/kg、5g/kg、10g/kg的剂量体内用药,对ConA诱导的小鼠的T细胞的增殖反应有增强作用,而对LPS诱导的小鼠B细胞的增殖反应效果不显著。香菇多糖是已知的免疫增强剂,生精固本丸与之相比作用相似。2.3生精固本丸对小鼠游泳耗竭的影响结果见表3。表3生精固本丸对小氧游泳耗竭的影响注:与对照组相比*P<0.05,P<0.001结果表明,动物给药5g/kg、10g/kg,连用4d,游泳耗竭时间分别为15.1±3.5及35.0±5.3min,与对照组相比均有显著性差异,表明本品具有较强的抗疲劳作用。而给药2.5g/kg时,与对照组相比则无明显差异,提示本品具有明显的量效关系。
P<0.01 Results As shown in Table 2, Shengjing Guben Pills were administered at a dose of 2.5 g/kg, 5 g/kg, and 10 g/kg to the body, which enhanced the proliferation of T cells induced by ConA-induced mice. However, the effect of LPS-induced proliferation of mouse B cells was not significant. Lentinan is a known immunopotentiator, and Shengjing Gubenwan has a similar effect. 2.3 Effect of Shengjing Gubenwan on swimming depletion in mice See Table 3. Table 3 Effects of Shengjing Guben Pills on Oxygen Swimming Depletion Note: *P<0.05 compared with control group, P<0.001 Results show that animals were administered 5g/kg, 10g/kg, used for 4 days, swimming Depletion time was 15.1±3.5 and 35.0±5.3 min, respectively, and there was a significant difference compared with the control group, indicating that this product has a strong anti-fatigue effect. When administered 2.5 g/kg, there was no significant difference compared with the control group, suggesting that the product has a significant dose-effect relationship.