患者男,40岁。左足内侧两处褐色斑块10年余,门诊行手术切除,皮损组织病理示:角化不全,棘层肥厚,皮损部位细胞胞浆较透明,与正常角质细胞界限明显,PAS染色阳性,具有透明细胞棘皮瘤典型的病理表现。 Male patient, 40 years old. More than 10 years of brown plaque on the inside of the left foot, surgically removed surgery, histological lesions showed: hyperkeratosis, stratum hypertrophy, skin lesions more transparent cytoplasm, with clear boundaries of normal keratinocytes, positive PAS staining, With clear cell acanthoma typical pathological manifestations.