目的　探讨使用伽玛刀治疗原发性三叉神经痛的方法和疗效。方法　采用国产旋转式伽玛刀治疗原发性三叉神经痛患者 ,照射靶点为三叉神经感觉根 ,4mm准直器 ,2～ 3个等中心点 ,中心剂量 70～ 90Gy。结果　随访 3～ 18个月 ,有效率 88% ,无放射性水肿、神经功能缺失、脑干损伤等并发症。结论　伽玛刀治疗原发性三叉神经痛效果满意 ,安全性高 ,可以作为原发性三叉神经痛的首选治疗方法。 Objective To explore the method and efficacy of gamma knife treatment of primary trigeminal neuralgia. Methods The domestic rotary gamma knife was used to treat patients with primary trigeminal neuralgia. The irradiation target was the sensory root of trigeminal nerve, 4mm collimator, 2 ~ 3 isocenters, and the central dose was 70-90 Gy. Results The follow-up ranged from 3 to 18 months, with an effective rate of 88%. No radiological edema, neurological deficit and brain stem injury were observed. Conclusion Gamma knife treatment of primary trigeminal neuralgia with satisfactory results, high safety, can be used as the primary treatment of primary trigeminal neuralgia.