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1例68岁男性糖尿病、肾病患者,因腹泻使用万古霉素0.5g溶于0.9%氯化钠注射液250ml中静脉滴注,1次/d。3d后,患者的WBC和N分别由14.3×109/L和0.90下降至1.1×109/L和0.45。停用万古霉素,皮下注射非格司亭150μg。第2天患者因低血压休克死亡。
A 68-year-old man with diabetes and nephropathy was infused intravenously with 0.5 ml of vancomycin 0.5 g dissolved in 0.9% sodium chloride injection 250 ml once daily. After 3 days, the WBC and N decreased from 14.3 × 109 / L and 0.90 to 1.1 × 109 / L and 0.45, respectively. Vancomycin was discontinued and 150 μg of filgrastim was injected subcutaneously. On the second day, the patient died of hypotension.