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“霰弹理论”认为中药作用机制和途径表现为多向性、多层面、多靶点的药理学特点 ,这些特点决定了中药复方中任何一种单一组分均可具有微小的生物学效应。在药物组分之间的相互作用中 ,除了少数已证明具有受体效应的组分外 ,多数组分是微效组分 ,即 :中药药效 =A +B +C +…N个微小效应的累加作用。对某一组分不能忽略其生物学的微小效应 ,也不能采用简单的检测手段和数学统计方法分析微小效应。采用细胞培养的方法结合数学概率论将组分的微小生物学效应合并成机体的整体的生物学效应 ,可以解决实验医学与中医结合中遇到的理论与实际相脱节、实验研究结果与临床效果相背离等问题。
“Shotgap theory” that the mechanisms and pathways of Chinese medicine performance for the multi-directional, multi-level, multi-target pharmacological characteristics, these characteristics determine the traditional Chinese medicine compound any one single component can have a small biological effects. In the interaction between the drug components, most of the components are the minor components except for the few components that have been shown to have the receptor effect, namely: Chinese medicine efficacy = A + B + C + ... N tiny effects The cumulative effect. For a component can not ignore the micro-effects of its biology, can not be a simple means of detection and mathematical statistical methods to analyze the micro-effects. Using the method of cell culture combined with mathematical probability theory to combine the microbiological effects of the components into the overall biological effect of the organism, the theoretical and practical problems encountered in the combination of experimental medicine and Chinese medicine can be solved, and the experimental research results and clinical effects Departure and other issues.