目的探讨瑞芬太尼复合丙泊酚在无痛胃镜检查中的应用。方法60例进行无痛胃镜检查患者,随机分为瑞芬太尼加丙泊酚组和芬太尼加丙泊酚组,观察两组麻醉后生命体征变化、体动反应、苏醒时间。结果两组生命体征变化无明显差异,瑞分组体动反应发生率低、苏醒时间短。结论瑞芬太尼复合丙泊酚麻醉在无痛胃镜检查中应用是可靠的。 Objective To investigate the application of remifentanil combined with propofol in painless gastroscopy. Methods Sixty patients undergoing painless gastroscopy were randomly divided into remifentanil plus propofol group and fentanyl plus propofol group. Changes in vital signs, body movement and wakefulness after anesthesia were observed in both groups. Results There was no significant difference in the change of vital signs between the two groups. The incidence of body movement reaction in Rui-sub group was low and the recovery time was short. Conclusion The application of remifentanil combined with propofol anesthesia in painless gastroscopy is reliable.