植入前遗传学诊断是在胚胎着床前对其遗传物质进行分析,结合体外受精和胚胎移植技术,选择正常的胚胎进行移植的一门新兴的辅助生殖技术,该技术在遗传病的诊断中占有越来越重要的地位。截至到2005年10月世界上已有1959例正常婴儿通过植入前诊断技术诞生。总结Duchenne型肌营养不良症植入前遗传学诊断的步骤和各项技术,并对其目前存在的问题和解决方法以及其应用前景进行讨论。 Preimplantation genetic diagnosis is the analysis of genetic material prior to implantation of the embryo, in combination with in vitro fertilization and embryo transfer techniques, an emerging assisted reproductive technique for selecting normal embryos for transplantation, which is used in the diagnosis of genetic diseases Occupy more and more important position. As of October 2005, 1959 normal infants worldwide have been established by preimplantation diagnostic techniques. To summarize the steps and techniques of preimplantation genetic diagnosis of Duchenne muscular dystrophy, and to discuss its existing problems and solutions as well as their application prospects.