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心房颤动(atrialfibrillation,AF)是一种自身进展性疾病,即具有自身延续性(self-perpetuating)。1995年,Wijffels等首次提出心房电重构概念,即随AF持续时间延长,心房肌电生理特性发生改变,主要表现为心房有效不应期(atrialeffectiverefractoryperiod,AERP)缩短、AERP频率适应性
Atrial fibrillation (AF) is a self-progressing disorder that is self-perpetuating. In 1995, Wijffels et al. First proposed the concept of atrial electrical remodeling. That is, the electrophysiological characteristics of atrial myocardium changed with the prolongation of AF duration. The changes of atrial electrophysiological refraction period (AERP), AERP frequency adaptability