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【目的】比较外科手术与介入术治疗糖尿病下肢缺血病变的临床疗效。【方法】选取2011年6月至2013年6月本院收治的糖尿病下肢缺血病变患者113例，根据 T ASCⅡ分级及治疗方式将其分为四组：T ASCⅡC级30例（C级手术组）、T ASCⅡD级27例（D级手术组）行股‐腘动脉旁路移植术；T ASCⅡC级组29例（C级介入组）、T ASCⅡD级组27例（D级介入组）行支架植入术；观察四组术后1周、3个月、6个月、1年的下肢血管通畅率、踝肱指数（ABI），记录四组生存率、保肢率、并发症发生率。【结果】术后1周、3个月，手术组与介入组下肢血管通畅率、ABI比较无统计学差异（ P ＞0．05）；术后6个月、1年手术组通畅率、ABI均高于介入组（P ＜0．05）；四组保肢率、生存率比较差异无统计学意义（P ＞0．05）；手术组并发症发生率低于介入组（ P ＜0．05）。【结论】外科手术与介入术治疗糖尿病下肢缺血病变的保肢率、生存率相近，但外科手术的远期疗效优于介入术。“,”[Objective] To compare the efficacies of surgery versus interventions for diabetic mellitus with lower limb ischemic .[Methods] A total of 113 patients of diabetic mellitus with lower limb ischemic were di‐vided into four groups of TASCⅡC surgery ( n =30) ,TASCⅡD surgery ( n =27) ,TASCⅡC intervention ( n=29) and TASCⅡD intervention ( n=27) .The surgery was femoro‐popliteal artery bypass grafting while intervention stenting .For four groups ,the parameters of patency rate ,ankle‐brachial index (ABI) ,rates of survival ,limb salvage and complications were recorded at 1 week ,3 months ,6 months and 1 year .[Results]After 1 week and 3 months ,surgery and intervention groups showed no significant difference in patency rate or ABI ( P >0 .05) .At 6 months and 1 year ,patency rate and ABI were higher in surgery group than those in intervention group ( P0 .05) .And complication rate was lower in surgery group than that in interven‐tion group ( P < 0 .05) .[Conclusion] Surgery and interventional stenting have similar rates of limb salvage and survival .However ,surgery offers better long‐term efficacies .