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目的了解浙江省开化县中、小学学生病毒性乙型肝炎(乙肝)病毒(HBV)感染状况,评价乙肝疫苗的接种效果。方法对新入校6477名学生进行HBV血清学检测。结果学生HBV表面抗原(HBsAg)阳性率为4.54%,男生高于女生,农村高于城镇,中学生高于小学生;HBV表面抗体(抗-HBs)阳性率为37.30%,女生高于男生,城镇高于农村,小学生高于中学生;易感人群占学生人数的60.80%。结论学校对入校新生应进行体检,检测肝功能和乙肝标志物,对已感染并具有一定传染性的学生,学校要做好管理工作,对乙肝标志物阴性的易感者应加强乙肝疫苗接种。
Objective To understand the status of viral hepatitis B (HBV) infection among primary and secondary school students in Kaihua County, Zhejiang Province and evaluate the vaccination effect of hepatitis B vaccine. Methods 6477 new students were enrolled in HBV serology test. Results The positive rate of HBV surface antigen (HBsAg) was 4.54% in boys, higher in girls than in girls, higher in rural areas than in urban areas and higher in middle school students than in primary school students. The positive rate of anti-HBs was 37.30% In rural areas, primary school students are higher than secondary school students; susceptible people make up 60.80% of the total number of students. Conclusions The school should take physical examination, detect liver function and hepatitis B markers for freshmen who have been admitted to school. For those students who have been infected and have certain contagiousness, the school should do well in management and hepatitis B vaccination should be strengthened for those who are negative for HBV markers.