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目的:探索中药藿香正气水肠道作用机理。方法:运用肌肉张力测量技术研究藿香正气水对大鼠结肠平滑肌收缩的影响。结果:藿香正气水能够抑制由激动剂—卡巴胆碱(CCH)和KCl引起大鼠结肠平滑肌的收缩。结论:藿香正气水抑制收缩的作用与抑制平滑肌细胞膜上钙通道的开放是相关的。
Objective: To explore the action mechanism of Chinese medicine Huoxiang Zhengqi Water Intestinal. Methods: The effects of Huoxiangzhengqi water on contraction of rat colonic smooth muscle were studied by muscle tension measurement. Result: Huoxiangzhengqi water can inhibit the contraction of rat colonic smooth muscle induced by agonists carbachol (CCH) and KCl. Conclusion: Huoxiangzhengqi water can inhibit the contractile effect of calcium channel on smooth muscle cell membrane is related to the opening.