奥司他韦(达菲)是瑞士巴塞尔豪夫迈-罗氏制药有限公司(罗氏公司)研发的一种有效、稳定和选择性的甲型和乙型流感病毒神经氨酸酶抑制剂,口服用于治疗和预防流行性感冒(流感)。达菲口服后经肝脏和肠道酯酶迅速催化转化为其活性代谢物奥司他韦羧酸盐。奥司他韦羧酸盐能选择性结合和抑制流感病毒神经氨酸酶,阻止病毒颗粒从被感染 Oseltamivir (Tamiflu) is an effective, stable and selective influenza A and B virus neuraminidase inhibitor developed by Hauppauge-Roche Pharmaceuticals Ltd. (Roche) of Basel, Switzerland. Oral For the treatment and prevention of influenza (flu). Tamiflu orally after the liver and intestinal esterase rapid catalytic conversion to its active metabolite oseltamivir carboxylate. Oseltamivir carboxylate selectively binds to and inhibits influenza virus neuraminidase, preventing viral particles from becoming infected