论文部分内容阅读
目的 :引进国家卫生部推广的“十年百项计划”项目———幽门螺杆菌根除最佳方案 :含果胶铋四联疗法。旨在观察该方法治疗幽门螺杆菌阳性消化性溃疡的临床疗效。方法 :应用含果胶铋四联疗法 (果胶铋 0 .2tid、奥美拉唑 2 0mgbid、阿莫西林 0 .5tid和甲硝唑 0 .4tid)治疗幽门螺杆菌阳性消化性溃疡 5 6例 ,疗程为 1周。结果 :溃疡愈合 2 6例 (46 .4 3% )、基本愈合 18例 (32 .14 % ) ,有效 10例 (17.86 % ) ,无效 2例 (3.75 % ) ,总有效率 96 .4 3% (5 4 / 5 6 ) ,溃疡愈合率 78.5 7% ,幽门螺杆菌根除率 92 .86 % ,症状缓解率 10 0 % ,轻度药物反应2 5 %。结论 :含果胶铋四联疗法治疗幽门螺杆菌阳性消化性溃疡疗效可靠 ,幽门螺杆菌根除率及溃疡愈合率均高于含铋剂三联疗法 ,符合卫生部提出的高效、安全、疗程短、价廉的根治幽门螺杆菌的治疗标准 ,值得推广应用。
OBJECTIVE: To introduce the “10-year Hundred Plans” project promoted by the Ministry of Health --- Helicobacter pylori eradication program: pectin-bismuth quadruple therapy. To observe the method of treatment of Helicobacter pylori-positive peptic ulcer clinical curative effect. Methods: Forty five cases of positive Helicobacter pylori-associated peptic ulcer were treated with bismuth-pectin-containing pectin (pectin bismuth 0.2id, omeprazole 20mgbid, amoxicillin 0. 5tid and metronidazole 0. 4tid) , Treatment for 1 week. Results: The ulcer healed in 26 cases (46.43%), basically healed in 18 cases (32.14%), effectively in 10 cases (17.86%), invalid in 2 cases (3.75%), and the total effective rate was 96.43% (54/56), ulcer healing rate 78.5 7%, Helicobacter pylori eradication rate 92.86%, symptom remission rate 10 0% and mild drug reaction 25%. Conclusion: The pectin bismuth quadruple therapy for the treatment of Helicobacter pylori-positive peptic ulcer is reliable, the eradication rate of Helicobacter pylori and ulcer healing rate are higher than the bismuth-containing triple therapy, in line with the Ministry of Health proposed efficient, safe, short course of treatment, Cheap cure Helicobacter pylori treatment standards, it is worth promoting application.