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目的研究微生态制剂(金双歧)对危重病患者胃肠功能障碍恢复的治疗作用及多器官功能障碍综合征(MODS)的防治。方法96例ICU胃肠功能障碍的危重病患者,分为两组:金双歧治疗组(56例),对照组(40例),观察两组患者胃肠功能评分、Marshall评分、APACHEⅡ评分、MODS的发生率与病死率。结果金双歧治疗组治疗后胃肠功能评分、APACHEⅡ评分及Marshall评分均有所降低,MODS的发生率和病死率均与对照组差异有统计学意义(P<0.01)。结论微生态制剂对危重病患者胃肠功能障碍具有较好的治疗作用,可明显降低MODS的发生率和病死率。
Objective To study the therapeutic effect of probiotics (Jinshuangqi) on the recovery of gastrointestinal dysfunction in critically ill patients and the prevention and treatment of multiple organ dysfunction syndrome (MODS). Methods A total of 96 critically ill patients with gastrointestinal dysfunction in ICU were divided into two groups: Jinshuangqi group (56 cases) and control group (40 cases). The gastrointestinal function score, Marshall score, APACHE Ⅱ score and MODS Incidence and mortality. Results The scores of gastrointestinal function, APACHEⅡscore and Marshall score decreased after treatment in the bifidobacterium treatment group, and the incidence of MODS and mortality were significantly different from the control group (P <0.01). Conclusion The probiotics have a good therapeutic effect on gastrointestinal dysfunction in critically ill patients, and can significantly reduce the incidence of MODS and mortality.