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目的观察高强度聚焦超声联合小剂量米非司酮治疗子宫腺肌病的临床效果。方法选取该院2012年1月-2013年12月收治的子宫腺肌病患者204例,随机分为观察组和对照组各102例。观察组采用高强度聚焦超声联合小剂量米非司酮治疗,对照组单纯采用高强度聚焦超声治疗。治疗后比较2组患者的血色素(Hb)、子宫体积、病灶体积、痛经改善情况。结果治疗后12个月观察组患者的Hb高于对照组,子宫体积、病灶体积均小于对照组,患者的疼痛程度明显优于对照组,差异均有统计学意义(P<0.05)。结论高强度聚焦超声联合小剂量米非司酮治疗子宫腺肌病效果较好,可显著缩小子宫体积及病灶体积,缓解痛经,值得临床推广应用。
Objective To observe the clinical effect of high intensity focused ultrasound combined with low dose mifepristone in the treatment of adenomyosis. Methods 204 cases of adenomyosis admitted from January 2012 to December 2013 in our hospital were randomly divided into observation group and control group with 102 cases each. Observation group using high-intensity focused ultrasound combined with low-dose mifepristone treatment, the control group was treated with high-intensity focused ultrasound. After treatment, the hemoglobin (Hb), uterine volume, lesion volume and dysmenorrhea in two groups were compared. Results In the 12 months after treatment, the Hb in the observation group was higher than that in the control group. The volume of the uterus and the volume of the lesion in the observation group were smaller than those in the control group. The pain degree was significantly better in the observation group than in the control group (P <0.05). Conclusion High-intensity focused ultrasound combined with low-dose mifepristone treatment of adenomyosis better, can significantly reduce the size of the uterus and lesion volume, relieve dysmenorrhea, is worthy of clinical application.