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为探讨一氧化氮(NO)在小儿支气管肺炎中的变化及其作用,测定了28例患儿血清NO_2~-/NO_3~-含量。结果表明;肺炎急性期患儿血清NO水平较对照组显著增高(P<0.05)。重症型较普通型更明显(P<0.05),并且血清NO的变化与丙二醛(MDA)的变化趋向相同。无论普通型肺炎还是重症肺炎,患儿血清NO、MDA水平在恢复期均降至对照组水平。本文提示,NO在小儿支气管肺炎发生发展中起重要作用。本文还对NO水平升高的意义作了初步分析。
In order to investigate the change and its role of nitric oxide (NO) in children with bronchial pneumonia, the serum levels of NO 2 - / NO 3 - in 28 children were measured. The results showed that serum nitric oxide levels in children with acute pneumonia were significantly higher than those in the control group (P <0.05). The severe type was more obvious than the normal type (P <0.05), and the change of serum NO was the same as that of malondialdehyde (MDA). Regardless of common type of pneumonia or severe pneumonia, children with serum NO, MDA levels were reduced to the control group during the recovery period. This article suggests that NO plays an important role in the development of bronchial pneumonia in children. This article also made a preliminary analysis of the significance of the elevated NO level.