缺血性脑血管病已成为我国居民主要致死、致残性疾病~([1]),并且缺血性脑血管病患者的脑卒中再发风险更高~([2])。动脉粥样硬化性疾病是一种可累及机体多处血管床的慢性系统性炎性病变。研究显示,缺血性脑血管病的发生与动脉粥样硬化性病变密切相关~([3])。在中国,33%~50%的急性缺血性脑卒中是由颅内动脉粥样硬化性疾病(intracranial atherosclerotic disease,ICAD)导致的~([4-5]),并且颈动脉粥样硬化也已经被确认 Ischemic cerebrovascular disease has become the major lethal and disabling disease in China’s residents ([1]), and the risk of recurrent stroke in patients with ischemic cerebrovascular disease is higher (2). Atherosclerotic disease is a chronic systemic inflammatory disease that can affect multiple vascular beds in the body. Studies have shown that the occurrence of ischemic cerebrovascular disease and atherosclerotic lesions are closely related to ~ ([3]). In China, 33% to 50% of acute ischemic stroke is caused by intracranial atherosclerotic disease (ICAD) ~ ([4-5]), and carotid atherosclerosis Has been confirmed