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胃肠道间叶源性肿瘤中最常见病理类型是胃肠道间质瘤(GIST),是临床表现为全消化道(食道到直肠)罹患的间叶源性肿瘤的其中一类。其来源于组织结构相对未分化的间叶细胞。据相关研究认为,作为非上皮源性肿瘤的胃肠道间质瘤主要起源是消化道中免疫组化表达CD117阳性的、组织形态富于梭形、上皮形或多形性细胞的间叶干细胞。近年来GIST其诊断、鉴别诊断及治疗仍较为困难[1]。我院自2007年1月至2012年6月共收治重症胃肠道间质瘤21例,并对其临床
The most common pathological type of gastrointestinal mesenchymal tumors is gastrointestinal stromal tumors (GISTs), one of the most clinically apparent mesenchymal tumors of the digestive tract (esophagus to rectum). It is derived from relatively undifferentiated mesenchymal cells of the tissue structure. According to the relevant research, the main origin of gastrointestinal stromal tumors as non-epithelial tumors is the mesenchymal stem cells with immunohistochemical expression of CD117 in the digestive tract, which are rich in fusiform, epithelial or pleomorphic cells. In recent years, GIST diagnosis, differential diagnosis and treatment is still more difficult [1]. Our hospital from January 2007 to June 2012 were treated 21 cases of severe gastrointestinal stromal tumors, and its clinical