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以黑米水提液、黑米醇提液、螺旋藻悬液给老龄ＢＡＬＢ／Ｃ小鼠每日每只灌胃１ｍｌ经４５～６０天后，测定其皮肤及尾腱中的羟脯氨酸（ＨｙＰ）的含量及全血谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）的活力。结果表明黑米水提液、黑米醇提液能显著提高小鼠皮肤中ＨｙＰ含量（Ｐ＜０．０１，Ｐ＜０．０５），黑米水提液能显著提高小鼠尾腱中ＨｙＰ的含量（Ｐ＜０．０５），而黑米醇提液对小鼠尾腱中的ＨｙＰ含量无明显影响（Ｐ＞０．０５）；黑米水提液和醇提液均能显著提高小鼠全血ＧＳＨ－Ｐｘ的活力（Ｐ＜０．０５）。
The aged mice were treated with black rice extract, black rice alcohol extract, and spirulina suspension for 1 hour in each of the old BALB/C mice. After 45 to 60 days, the hydroxyproline in the skin and tail cercariae was measured ( HyP) content and whole blood glutathione peroxidase (GSH-Px) activity. The results showed that black rice water extract and black rice alcohol extract can significantly increase the content of HyP in mouse skin (P<0.01, P<0.05). Black rice extract can significantly increase HyP in mice. (P<0.05), but the black rice extract had no significant effect on the HyP content in the mice (P>0.05); the black rice water extract and the alcohol extracts could both increase significantly. The activity of GSH-Px in rat whole blood (P<0.05).