TORCH是一组能引起先天性感染的病原生物体,包括弓形虫(TOXO),风疹病毒(RV),巨细胞病毒(CMV),单纯疱疹病毒(HSV)。先天性感染是指宫内发育的胎儿通过胎盘获得的感染。感染的途径主要是经过胎盘循环引起母儿间的垂直传播,也可是经孕妇的生殖道上行扩散。孕妇感染后大多数无典型的临床症状,但胎儿发生感染会有严重后果。 TORCH is a group of pathogens that cause innate infections, including TOXO, rubella (RV), cytomegalovirus (CMV) and herpes simplex virus (HSV). Congenital infection refers to the fetus acquired intrauterine infection obtained through the placenta. The main route of infection is caused by placental circulation between mother and child vertical transmission, but also through the reproductive tract of pregnant women on the line of proliferation. Most pregnant women do not have typical clinical symptoms of infection, but fetal infection can have serious consequences.