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作者分别测定了３５例乙型肝炎后肝硬变患者的免疫球蛋白（ＳＩｇ），Ｔ细胞亚群、巨噬细胞吞噬功能，并随机分成两组，给予高血糖素或胰岛素治疗，两周后复查，高血糖素组ＩｇＧ１４．３９±５．０３ｇ／Ｌ，ＩｇＡ２．０４±０．６１ｇ／Ｌ，ＩｇＭ１．８２±０．８７ｇ／Ｌ，ＣＤ￣＋－３５６．１５±８．５８％，ＣＤ￣＋－４４５．８５±７．９４％，ＣＤ￣＋－８４１．９４±５．８２％，ＣＤ￣＋－４／ＣＤ￣＋－８１．１２±０．１２，巨噬细胞吞噬率５２．２９±８．６４％，吞噬指数为１．０２±０．２４．较胰岛素组及同组治疗前比较，ＳＩｇ下降、Ｔ细胞升高，Ｔ亚群比例改善、巨噬细胞功能增强，特别是ＩｇＧ（Ｐ＜０．０５），ＣＤ￣＋－８Ｐ＜０．０１），ＣＤ￣＋－４／ＣＤ￣＋－８（Ｐ＜０．０５）及巨噬细胞吞噬率（Ｐ＜０．０５）变化显著．提示高血糖素对肝硬变患者免疫功能有一定的调节意义．
The authors measured the immunoglobulin (SIg), T cell subsets, macrophage phagocytosis in 35 patients with posthepatitic cirrhosis and were randomly divided into two groups, given glucagon or insulin therapy, and two weeks later Review, glucagon group IgG14.39 ± 5.03g / L, IgA2.04 ± 0.61g / L, IgM1.82 ± 0.87g / L, CD ~ + -356.15 ± 8.58%, CD + -445.85 ± 7.94%, CD ~ + -841.94 ± 5.82%, CD ~ + -4 / CD ~ + -81.12 ± 0.12, macrophage phagocytosis rate 52. 29 ± 8.64% and phagocytic index 1.02 ± 0.24. Compared with the insulin group and the same group before treatment, SIg decreased, T cells increased, the proportion of T subgroups improved, macrophage function enhanced, especially IgG (P <0.05), CD ~ + -8P <0.01 ), CD ~ + -4 / CD ~ + -8 (P <0.05) and macrophage phagocytosis rate (P <0.05). Prompted glucagon immune function in patients with cirrhosis have a certain regulatory significance.