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在溶栓治疗开展前的几项研究表明,室性心律失常的存在是急性心肌梗塞(AMI)恢复期患者死亡率的独立危险因素。鉴于纤溶治疗影响梗塞的自然进程,并且可能改变各种危险因素的临床相关性,本研究旨在确定心肌梗塞(MI)后急性期使用纤溶剂治疗的患者室性心律失常的发生率及其预后价值。方法和结果对8676例 MI 后患者出院前行24小时 Holter 记录,分析室性心律失常的存在。随访患者至急性发作后6个月,统计总死亡率和心血管猝死率;计算分析单变量和多变量的相对危险性。64.1%的患者有室性心律失常,19.7%的患者记录到10次/小时以上的
Several studies prior to thrombolytic therapy have shown that the presence of ventricular arrhythmias is an independent risk factor for mortality in patients recovering from acute myocardial infarction (AMI). In view of the natural progression of fibrinolysis affecting infarction and the potential for altering the clinical relevance of various risk factors, this study aimed to determine the incidence of ventricular arrhythmias in patients treated with fibrinolytic agents at acute stage following myocardial infarction (MI) Prognostic value. Methods and Results A total of 8676 MI patients were discharged 24 hours Holter recording before discharge to analyze the existence of ventricular arrhythmia. The patients were followed up to 6 months after the onset of acute exacerbation, and the total mortality and the rate of sudden cardiac death were calculated. The relative risk of univariate and multivariate analysis was calculated and analyzed. 64.1% of patients had ventricular arrhythmias, 19.7% of patients recorded more than 10 times / hour