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目的 研究肿瘤特异生长因子检测在肿瘤诊断及治疗效果观察中应用的意义。方法 采用比色法对 2 0 9例恶性肿瘤患者 ,33例正常人 ,15例良性瘤患者及部分恶性肿瘤患者治疗后血清肿瘤特异生长因子 (TumorSpecificGrowthFacter,TSGF)进行检测分析。结果 恶性肿瘤患者血清TSGF浓度明显高于正常对照组和良性肿瘤患者 ,并且恶性肿瘤患者治疗后血清TSGF浓度明显比治疗前低。血清TSGF测定对恶性肿瘤诊断的敏感性为 80 9% ,特异性为 93 2 %。结论 血清TSGF检测对恶性肿瘤的早期诊断 ,病情观测 ,疗效观察及预后有重要意义。
Objective To study the significance of detection of tumor specific growth factor in the observation of tumor diagnosis and treatment. Methods The colorimetric method was used to detect the Tumor Specific Growth Fetter (TSGF) after treatment in 209 patients with malignant tumors, 33 normal controls, 15 benign tumors and some malignant tumors. Results Serum TSGF levels in patients with malignant tumors were significantly higher than those in normal controls and benign tumors, and serum TSGF levels in patients with malignant tumors were significantly lower than those before treatment. Serum TSGF assay for the diagnosis of malignant tumors was 80 9%, specificity 93 2%. Conclusion The serum TSGF detection is of great significance for the early diagnosis of malignant tumors, observation of the disease, observation of the curative effect and prognosis.