由于生长激素(GH)水平测定技术的进展,使肢端肥大症能够早期作出诊断,并且还能用以判断疗效.本文根据132例肢端肥大症手术病例的术前、术后GH水平测定结果为基础对本病的临床、放射学表现、内分泌改变、手术发现、疗效相互之间的关系进行了分析.〔临床资料〕本组病例:男65例,女67例,均为成人(20～67岁),30岁以下,男多于女;30～59岁,男女相等;60岁以上则女多于男.全部病例均有程度不等的肢端肥大表现(包括面部及肢端改变),但面部与肢端,手与足的改变可不一致,往往以某一方面表现突出,常见症状为头痛(男37%,女48%),闭经(35例经绝前期妇女有18例闭经).本组病例视野缺损较少见(15%).其他合并症有糖尿病(11%)、甲亢(8%),心机能不全(11%)和高血压等.放射学检查包括蝶鞍后前位及侧位体层摄影及 Because of the progress in the determination of growth hormone (GH) levels, acromegaly can be diagnosed early, and can also be used to judge the efficacy. This article according to 132 cases of acromegaly in surgical cases of preoperative and postoperative GH measurement results Based on the clinical, radiological performance, endocrine changes, surgical findings, efficacy of the disease were analyzed. [Clinical data] This group of cases: 65 males and 67 females, all adults (20 ~ 67 years old), 30 years of age, men more than women; 30-59 years old, men and women equal; over 60 years of age than women. All cases have varying degrees of acromegaly performance (including facial and extremities changes) , but the facial and acral, hand and foot changes can be inconsistent, often prominent in a certain area, the common symptoms are headache (men 37%, women 48%), amenorrhea (35 cases of premenopausal women with amenorrhea in 18 cases) The visual field defect in this group of patients is rare (15%). Other complications include diabetes (11%), hyperthyroidism (8%), cardiac insufficiency (11%) and high blood pressure. Radiological examinations include the posterior of the sella. Position and lateral tomography and