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AIM: To investigate the protective effects of N-acetyl-cysteine (NAC) and N~ω-Nitro-L-arginine methyl ester(L-NAME) on aluminium phosphide (AlP) poisoninginduced hemodynamic changes, myocardial oxygen freeradical in injury and on survival time in rats. METH-ODS: AlP (12.5 mg/kg) was administered intragastri-cally under urethane anaesthesia. The effect of pre- andpost-treatment with NAC and L-NAME alone and incombination was studied on haemodynarnic parameters[blood pressure (BP), heart rate (HR), and electrocar-diogram (ECG) ] and biochemical parameters (malonyl-
AIM: To investigate the protective effects of N-acetyl-cysteine (NAC) and N ~ ω-Nitro-L-arginine methyl ester (L-NAME) on aluminum phosphide (AlP) poisoning induced hemodynamic changes, myocardial oxygen free radical in injury and on The effect of pre- and post-treatment with NAC and L-NAME alone and incombination was studied on haemodynarnic parameters [blood pressure (BP), heart rate (HR), and electrocar-diogram (ECG)] and biochemical parameters (malonyl-