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目的利用磁共振成像(MRI)探讨人眼调节时的晶状体及相关结构形态变化特点。设计前瞻性研究。研究对象健康志愿者。方法对8例健康志愿者11只正视眼分别在视近状态和视远状态进行MRI检查,对晶状体、前房及眼轴的MRI图像进行测量,调节前后晶状体及相关因素的变化进行配对t检验。主要指标晶状体的厚度、截面积,前房深度及眼轴长度。结果 11只正视眼视远时晶状体厚度、截面积、前房深度、眼轴平均为(3.51±0.20)mm、(22.89±1.82)mm2、(3.54±0.27)mm、(23.91±0.90)mm,视近时平均为(3.73±0.34)mm、(23.17±1.66)mm2、(3.29±0.32)mm、(23.82±1.07)mm,调节前后晶状体厚度、前房深度有显著性差异(t=3.563、P=0.007;t=4.804、P=0.001),晶状体截面积、眼轴差异无显著性(t=1.890、P=0.095;t=0.913、P=0.388),晶状体厚度差、前房深度差差异有显著性(P=0.000)。结论 MRI能反映晶状体在调节状态下的形态特点,有望成为研究人眼调节机制的重要方法之一。
Objective To investigate the morphological changes of the lens and related structures in the human eye by using magnetic resonance imaging (MRI). Design prospective studies. Study subjects healthy volunteers. Methods Eleven patients with ectopic eyes from 8 healthy volunteers were examined with MR imaging in the near and far states of vision. The MRI images of the lens, anterior chamber and ocular axis were measured. The changes of the phalanges and related factors were analyzed by paired t-test . The main indicators of the lens thickness, cross-sectional area, anterior chamber depth and axial length. Results The thickness, cross - sectional area and anterior chamber depth of the 11 eyes were (3.51 ± 0.20) mm, (22.89 ± 1.82) mm2, (3.54 ± 0.27) mm, (23.91 ± 0.90) mm, (3.73 ± 0.34) mm, (3.17 ± 1.66) mm2, (3.29 ± 0.32) mm and (23.82 ± 1.07) mm respectively. The thickness of the anterior chamber and the depth of the anterior chamber were significantly different (t = 3.563, (P = 0.007; t = 4.804, P = 0.001). There was no significant difference in axial cross-sectional area and axial length between the two groups (t = 1.890, P = 0.095; t = 0.913, P = 0.388) Significant (P = 0.000). Conclusion MRI can reflect the morphological characteristics of lens under the condition of adjustment, which is expected to become one of the important methods to study the regulation mechanism of human eye.