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目的探讨肝炎后肝硬化合并消化性溃疡采用倍他洛克联合奥美拉唑治疗的效果。方法 32例肝炎后肝硬化合并消化性溃疡患者,随机分为观察组与对照组,各16例。两组均采用抗纤维化、保肝等常规治疗,在此基础上对照组采用奥美拉唑等药物进行治疗,观察组在对照组基础上加用倍他洛克进行治疗,比较两组患者的治疗结果。结果观察组治疗总有效率显著高于对照组,差异具有统计学意义(χ~2=4.571,P<0.05)。观察组不良反应发生率显著低于对照组,差异具有统计学意义(χ~2=6.000,P<0.05)。结论采用倍他洛克联用奥美拉唑的治疗方式对肝炎后肝硬化合并消化性溃疡的治疗效果显著,治疗总有效率高,且不良反应发生率低,存在较高的临床应用价值。
Objective To investigate the effect of Betaloc and Omeprazole in the treatment of posthepatitic cirrhosis with peptic ulcer. Methods 32 patients with posthepatitic cirrhosis complicated with peptic ulcer were randomly divided into observation group and control group, with 16 cases in each group. Both groups were treated with routine anti-fibrosis and hepatoprotective methods. On the basis of this, the control group was treated with omeprazole and other drugs. The observation group was treated with Betaloc on the basis of the control group. The patients in both groups were compared Treatment results. Results The total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (χ ~ 2 = 4.571, P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (χ ~ 2 = 6.000, P <0.05). Conclusion The combination of betolo and omeprazole has a significant effect on the treatment of posthepatitic cirrhosis and peptic ulcer. The total effective rate of treatment and the low incidence of adverse reactions have high clinical value.