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目的探讨绝经后哈萨克族族女性骨代谢水平及生活方式的特点。方法选择符合研究对象的208名绝经后哈萨克族女性,测BMD、Ca、P、BAP、BGP、TRACP-5b、25-(OH)D3,按BMD值分为正常组,骨量减少组和骨质疏松组并进行比较。结果经单因素方差分析,各组中各自BGP、BAP、TRACP-5b、25-(OH)D3中有统计学意义(P<0.01),骨代谢水平与哈萨克族生活方式有关。结论骨代谢水平在哈萨克族绝经妇女中差异反应出绝经后妇女与生活方式、膳食结构有关,维生素D代谢上可能存在基因多态性影响。
Objective To investigate the characteristics of bone metabolism and lifestyle of Kazakh women in postmenopausal women. Methods A total of 208 postmenopausal Kazakh women who were eligible for the study were enrolled in this study. BMD, Ca, P, BAP, BGP, TRACP-5b and 25- (OH) D3 were measured and divided into normal group, Loose group and compare. Results One way analysis of variance (ANOVA) showed that BGP, BAP, TRACP-5b and 25- (OH) D3 in each group had statistical significance (P <0.01). The level of bone metabolism was related to Kazakh lifestyle. Conclusion The level of bone metabolism in postmenopausal women in Kazak ethnic group is different from that of postmenopausal women in terms of lifestyle and dietary structure. There may be genetic polymorphism in vitamin D metabolism.