论文部分内容阅读
目的 :研究肺鳞癌组织中DC的浸润程度及对预后的影响。方法 :将S 10 0蛋白作为DC的特异性标记物 ,应用SABC免疫学方法检测肺鳞癌组织中DC的分布。结果 :5 0例肺鳞癌中 ,DC显著浸润的 2 0例 ,5年生存率为 5 9%。轻度浸润的30例 ,5年生存率为 19 1%。 5 0例鳞癌中 ,低分化鳞癌 2 7例 ,DC显著浸润的 11例 ,5年生存率为 5 5 %。轻度浸润的 16例 ,5年生存率为 12 8%。高分化鳞癌 2 3例 ,DC显著浸润的 11例 ,5年生存率为 6 6 8%。轻度浸润的 12例 ,5年生存率为 2 7 2 %。经Log rank检验 ,在显著浸润和轻度浸润组二者之间有显著差异。结论 :肺鳞癌组织中DC显著浸润的预后明显好于轻度浸润的病例。
Objective: To study the infiltration of DC in lung squamous cell carcinoma and its prognosis. Methods: S 10 0 protein was used as a specific marker of DC. The distribution of DC in lung squamous cell carcinoma was detected by SABC immunological method. Results: Twenty cases of lung squamous cell carcinoma were significantly infiltrated with DC, and the 5-year survival rate was 59%. 30 cases of mild infiltration, 5-year survival rate of 19 1%. Fifty cases of squamous cell carcinoma, poorly differentiated squamous cell carcinoma in 27 cases, DC significantly infiltrated in 11 cases, 5-year survival rate was 55%. Sixteen cases were mild infiltration with a 5-year survival of 12.8%. There were 23 cases of well-differentiated squamous cell carcinoma, 11 cases of significant infiltration of DC, and 5-year survival rate of 6 6 8%. In 12 mild infiltrates, the 5-year survival rate was 272%. Log rank test showed significant difference between the two groups in significant infiltration and mild infiltration. Conclusion: The prognosis of patients with squamous cell carcinoma of lung squamous cell carcinoma is significantly better than that of mild infiltration.