大多数丙型肝炎病毒(HCV)感染患者常呈慢性过程乃至肝功能衰竭,故近年来HCV感染所致肝硬化也成为肝移植(LT)的适应证。然而,在LT病人中HCV病毒血症率和肝炎复发率分别高达95%和70%;巨细胞病毒(CMV)病毒血症与HCV感染病人LT后的异体移植失败有关。本文研究了β疱疹病毒在LT后HCV感染中的作用及CMV亚临床复制对HCV致病机制的影响。 Most patients with hepatitis C virus (HCV) infection often have chronic processes and even liver failure. Therefore, liver cirrhosis caused by HCV infection has become an indication of liver transplantation (LT) in recent years. However, rates of HCV viremia and hepatitis recurrence were as high as 95% and 70%, respectively, in LT patients; cytomegalovirus (CMV) viremia was associated with failed allografts after LT in HCV-infected patients. This article studies the role of β herpes virus in HCV infection after LT and the effect of CMV subclinical replication on the pathogenesis of HCV.