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近年来,人体内的金属中毒和微量金属的失衡(缺乏或积累过多)与疾病的关系愈来愈引起人们的关注。化学疗法是治疗这些疾病较为有效的方法。大量研究表明,金属络台物是一种具有极大潜力的无机新型药物,它具有传统药物无可比拟的性能。经过生物无机化学家、药物化学家和分子生物学家广泛深入的研究,采用近代合成技术和计算机模拟方法,一系列选择性高、毒性低、疗效显著的螯合剂和
In recent years, the relationship between human body’s metal poisoning and the imbalance of trace metals (lack or accumulation) and the disease has drawn more and more attention. Chemotherapy is a more effective method of treating these diseases. A large number of studies have shown that metal complex is a kind of inorganic new drug with great potential, which has the unparalleled performance of traditional drugs. After a wide range of in-depth research by bio-inorganic chemists, drug chemists and molecular biologists, using modern synthesis techniques and computer simulation methods, a series of chelators with high selectivity, low toxicity and significant curative effect and