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最近,IL-10抑制炎性肠疾病的原因及临床应用的可能性受到关注。IL-10主要是由2型T辅助细胞(Th2)产生的细胞因子,可使B细胞和肥大细胞的活性增强,而抑制巨噬细胞的抗原提呈能和细胞因子产生能。目前也认为IL-10可抑制1型T辅助细胞(Th1)产生细胞因子。Berg等对IL-10基因缺失的小
Recently, the cause of IL-10 inhibition of inflammatory bowel disease and the possibility of clinical application have drawn attention. IL-10 is mainly a cytokine produced by type 2 T helper cells (Th2), which enhances the activity of B cells and mast cells and inhibits the antigen-presenting and cytokine production of macrophages. It is also thought that IL-10 inhibits the production of cytokines by type 1 T-helper cells (Th1). Berg and other IL-10 gene deletion was small