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目的研究亚甲蓝术中定位胃癌前哨淋巴结的可行性。方法使用亚甲蓝对50例胃癌患者行术中前哨淋巴结定位及术中、术后活检。结果在50例中有49例(98%)找到前哨淋巴结。有15例前哨淋巴结存在转移,其中9例非前哨淋巴结也存在转移,6例前哨淋巴结为胃周淋巴结惟一转移部位。有34例前哨淋巴结无转移,其中8例非前哨淋巴结存在转移。结论使用亚甲蓝术中定位胃癌前哨淋巴结是确实可行的。在早期胃癌前哨淋巴结能准确预测胃癌淋巴结转移情况,有可能达到对没有淋巴结转移的胃癌患者,使其避免不必要的扩大性淋巴结清扫。
Objective To study the feasibility of localization of sentinel lymph nodes in methylene blue in gastric cancer. Methods Methylene blue in 50 cases of gastric cancer patients underwent sentinel lymph node mapping and intraoperative and postoperative biopsy. Results Of the 50 cases, 49 (98%) found sentinel lymph nodes. There were 15 cases of sentinel lymph node metastasis, including 9 cases of non-sentinel lymph node metastasis, 6 cases of sentinel lymph node is the only lymph node metastasis site. There were 34 cases of sentinel lymph node without metastasis, including 8 cases of non-sentinel lymph node metastasis. Conclusion The use of methylene blue in the localization of sentinel lymph nodes of gastric cancer is indeed feasible. In the early gastric cancer sentinel lymph node can accurately predict the status of lymph node metastasis of gastric cancer, it is possible to reach the no lymph node metastasis of gastric cancer patients, to avoid unnecessary expansion of lymph node dissection.