原发性胆囊癌的发病率有逐年上升趋势。本病被发现时往往已属于晚期，术后五年生存率仅５％～１２％左右。随着分子生物学的发展，发现癌基因ｃ－ｅｒｂＢ－２和肿瘤转移抑制基因ｎｍ２３Ｈ１是肿瘤发生、发展的相关基因。本研究采用免疫组织化学方法检测原发性胆囊癌中ｃ... The incidence of primary gallbladder cancer has increased year by year. When the disease was discovered, it was often advanced and the postoperative five-year survival rate was only about 5% to 12%. With the development of molecular biology, the oncogene c-erbB-2 and tumor metastasis suppressor gene nm23H1 were found to be related genes for tumorigenesis and development. This study used immunohistochemistry to detect primary gallbladder carcinoma c...