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目的:研究儿童脑肿瘤患者发病过程中,具体临床病理特点,从而便于对该病进行诊断及防治。方法:从2010年2月-2015年2月时间段,在我院选取儿童脑肿瘤患者共计300例开展调查,并对其临床病理特点进行可行性分析。结果:在所有选取300例患者中,共包括98例星形细胞瘤,所占患者总人数的32.7%;62例髓母细胞瘤,所占患者总人数的20.7%;51例室管膜瘤,所占患者总人数的17.0%;34例颅咽管瘤,所占患者总人数的11.3%;16例生殖细胞瘤,所占患者总人数的5.3%。儿童脑肿瘤患者,在临床表现方面具有抽搐、肢体瘫痪、呕吐及视力降低等方面的症状,首诊误诊率相对较高,能达到18.0%。在所有患者中,共有255例患者进行肿瘤全切,所占患者比例高达85.0%;33例患者进行次全切,所占患者比例为11.0%;9例患者进行大部分切除,所占患者比例为3.0%。共有120例患者采用放射治疗(40.0%),另有66例患者选择术后放疗(22.0%)。结论:相对而言,儿童脑肿瘤是一种恶性肿瘤疾病,患者本身临床症状较为复杂多样,而且该病具有误诊率高、周期长等方面的特点。通常来说,应进行选择手术治疗,同时开展术后放化疗。
Objective: To study the specific clinical and pathological features of brain tumor patients in childhood, so as to facilitate the diagnosis and prevention of the disease. Methods: From February 2010 to February 2015, a total of 300 cases of children with brain tumors were selected for investigation in our hospital and the feasibility of their clinical and pathological features was analyzed. Results: A total of 98 cases of astrocytomas were included in all selected 300 cases, accounting for 32.7% of the total number of patients; 62 cases of medulloblastoma, accounting for 20.7% of the total number of patients; 51 cases of ependymoma , Accounting for 17.0% of the total number of patients; 34 cases of craniopharyngiomas, accounting for 11.3% of the total number of patients; 16 cases of germinoma, accounting for 5.3% of the total number of patients. Child brain tumor patients, with clinical manifestations of convulsions, limb paralysis, vomiting and decreased visual acuity and other symptoms, the first diagnosis of misdiagnosis rate is relatively high, up to 18.0%. In all patients, a total of 255 patients underwent total tumor resection, accounting for up to 85.0% of the patients. 33 patients underwent total subtotal resection, accounting for 11.0% of the total; 9 of the 9 patients underwent resection, accounting for the proportion of patients Is 3.0%. A total of 120 patients treated with radiotherapy (40.0%), and another 66 patients chose postoperative radiotherapy (22.0%). Conclusion: Relatively speaking, brain tumor in children is a malignant tumor. The clinical symptoms of patients are complicated and diverse, and the disease has the characteristics of high misdiagnosis rate and long period. In general, should be selected surgical treatment, while conducting postoperative radiotherapy and chemotherapy.