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病人已经历一次或多次心肌梗塞。但他们的血胆固醇水平对预示可能生存或再次心肌梗塞发作有什么价值呢?5年研究表明“没有很大价值”。作者研究570例男性,平均51岁,均有一次或多次心肌梗塞病史。研究目的之一是确定雌激素、dextrothyroxin、菸酸、并用雌激素及菸酸,或并用雌激素及dextro-thyroxin,对心肌梗塞后病人的发病率及死亡率的作用。其次研究这些药物的药理作用。马雌激素(每天1.25毫克)对基线胆固醇水平(平均241毫克%)或心血管死亡率无作用。单用
The patient has experienced one or more myocardial infarctions. But what is the value of their blood cholesterol levels in predicting the likelihood of survival or reoccurrence of a myocardial infarction? Five years of research have shown “no great value.” The authors studied 570 men, mean 51 years, with one or more previous myocardial infarctions. One of the goals of the study was to determine the effects of estrogen, dextrothyroxin, nicotinic acid, estrogen and niacin, or estrogen and dextro-thyroxin on the morbidity and mortality of patients after myocardial infarction. Second, study the pharmacological effects of these drugs. Horse estrogen (1.25 mg daily) had no effect on baseline cholesterol levels (mean 241 mg%) or cardiovascular mortality. Single use