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目的观察环磷酰胺与紫三醇联合用药对治疗妇科肿瘤患者的临床效果。方法将我院妇科2010年6月-2013年2月间收治的妇科肿瘤患者88例,平均分为对照组和治疗组,其中对照组43例患者应用环磷酰胺治疗,治疗组43例患者在对照组基础上联合紫杉醇用药治疗。治疗结束后依据疗效评价标准对比两组患者进行综合评价。结果对照组患者病情发展9例(22.0%)、稳定21例(51.2%)、部分缓解3例(7.3%)、全缓解8例(19.5%),总有效率为26.8%;治疗组患者病情发展6例(14.6%)、稳定12例(29.3%)、部分缓解5例(12.2%)、完全缓解18例(43.9%),总有效率为56.1%。治疗组总有效率明显高于对照组,差异具有统计学意义。结论应用环磷酰胺与紫三醇联合用药对治疗妇科肿瘤具有较好的临床效果。
Objective To observe the clinical effect of combination of cyclophosphamide and triol on the treatment of patients with gynecologic cancer. Methods 88 cases of gynecologic oncology patients admitted to our hospital from June 2010 to February 2013 were divided equally into control group and treatment group, in which 43 patients in control group were treated with cyclophosphamide, and 43 patients in treatment group were treated with Control group based on the combination of paclitaxel medication. After treatment, the two groups of patients were evaluated according to the evaluation criteria. Results The patients in the control group developed in 9 cases (22.0%), stabilized in 21 cases (51.2%), partially relieved in 3 cases (7.3%), and totally eased in 8 cases (19.5%) with a total effective rate of 26.8% 6 cases (14.6%) were developed, 12 cases (29.3%) were stabilized, 5 cases (12.2%) partially relieved and 18 cases (43.9%) completely relieved. The total effective rate was 56.1%. The total effective rate of the treatment group was significantly higher than that of the control group, the difference was statistically significant. Conclusion The combination of cyclophosphamide and purple triol has good clinical efficacy in the treatment of gynecological tumors.