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目的观察熊去氧胆酸联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎的疗效。方法将82例非酒精性脂肪性肝炎(NASH)随机分为治疗组40例和对照组42例,治疗组用熊去氧胆加多烯酯磷脂酰碱治疗,对照组单用多烯酯磷脂酰碱治疗,疗程均为6个月。结果治疗组症状、肝功能、血脂、B超检查结果改善均优于对照组,两组疗效比较差异有统计学意义(P<0.05)。结论熊去氧胆酸联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎疗效好。
Objective To observe the efficacy of ursodeoxycholic acid combined with polyene phosphatidylcholine in the treatment of non-alcoholic steatohepatitis. Methods 82 cases of non-alcoholic steatohepatitis (NASH) were randomly divided into the treatment group of 40 cases and the control group of 42 cases, the treatment group with ursodeoxycholic acid plus phosphatidylcholine treatment, the control group alone with polyene ester phospholipid Physiotherapy, treatment are 6 months. Results The improvement of symptom, liver function, blood lipid and B-ultrasound in the treatment group were better than those in the control group. There was significant difference between the two groups in curative effect (P <0.05). Conclusion Ursodeoxycholic acid combined with polyene phosphatidylcholine treatment of non-alcoholic steatohepatitis effective.