异丙酚、氯胺酮静脉复合麻醉因麻醉效果确切、循环稳定和苏醒迅速已成为临床全凭静脉麻醉的手段之一。但复合麻醉中异丙酚和氧胺酮复合药量问题仍需探讨。本研究的目的是探讨不同剂量氯胺酮对异丙酚药效的影响，为临床合理用药提供科学依据。资料和方法一、一般资料．脊柱手术 Propofol, ketamine intravenous anesthesia due to the exact effect of anesthesia, circulatory stability and rapid recovery has become one of the means of clinical intravenous anesthesia. However, propofol and oxylamine compound drug dose in the compound anesthesia still need to be explored. The purpose of this study is to investigate the effects of different doses of ketamine on the pharmacodynamics of propofol and to provide a scientific basis for clinical rational drug use. Data and methods First, the general information. Spine surgery