论文部分内容阅读
目的探讨能谱CT在肝细胞癌与肝内肿块型胆管细胞癌鉴别诊断中的应用价值。方法行能谱CT扫描并经病理证实的肝癌患者34例(肝细胞癌20例、肝内肿块型胆管细胞癌14例),通过能谱分析软件,获取肿块内感兴趣区的碘基图、水基图及101组单能量图像,分析单能量55 Kev下对应的碘含量、水含量、能谱曲线及标准化后碘含量。用独立样本t检验分析上述参数。结果肝细胞癌的碘含量、能谱曲线斜率、标准化后碘含量分别为(12.84±2.38)、(1.58±0.24)、(0.15±0.05)μg/cm3,肝内肿块型胆管细胞癌分别为(10.71±3.01)、(1.34±0.32)、(0.12±0.34)μg/cm3。肝细胞癌与肝内肿块型胆管细胞癌的碘含量、能谱曲线斜率、标准化后碘含量差异均有统计学意义(P<0.05)。肝细胞癌与肝内肿块型胆管细胞癌的水含量分别为(1041.05±6.47)、(1 038.74±8.54)mg/cm3,差异无统计学意义(P>0.05)。结论能谱CT成像及多参数分析,对肝细胞癌与肝内肿块型胆管细胞癌鉴别诊断中有一定价值。
Objective To investigate the value of spectral CT in the differential diagnosis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Methods 34 cases of hepatocellular carcinoma (20 cases of hepatocellular carcinoma and 14 cases of intrahepatic cholangiocarcinoma) were diagnosed by pathological CT scan. The iodine-base diagram of the region of interest in the tumor was obtained by energy spectrum analysis software. Water base map and 101 single energy images. The corresponding iodine content, water content, energy spectrum curve and normalized iodine content under single energy 55 Kev were analyzed. The above parameters were analyzed by independent sample t-test. Results The iodine content, slope of energy spectrum curve and normalized iodine content of hepatocellular carcinoma were (12.84 ± 2.38), (1.58 ± 0.24) and (0.15 ± 0.05) μg / cm3 respectively. The intrahepatic cholestatic cholangiocarcinoma were ( 10.71 ± 3.01), (1.34 ± 0.32), (0.12 ± 0.34) μg / cm3. There were significant differences in iodine content, slope of energy spectrum curve and normalized iodine content between hepatocellular carcinoma and intrahepatic cholangiocarcinoma (P <0.05). The water content of hepatocellular carcinoma and intrahepatic cholangiocarcinoma were (1041.05 ± 6.47) and (1038.74 ± 8.54) mg / cm3 respectively, with no significant difference (P> 0.05). Conclusions Spectral CT imaging and multi-parameter analysis have certain value in the differential diagnosis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma.