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目的探讨胚胎发育不良性神经上皮瘤(DNT)的MRI表现及病理特征。方法对11例经手术病理证实的胚胎发育不良性神经上皮瘤MRI资料进行回顾性分析,并与低级别星形细胞瘤、少枝胶质细胞瘤、神经节细胞胶质瘤、蛛网膜囊肿等进行鉴别,重点研究DNT的发生部位、形态特征、MRI信号特点、强化方式等情况。结果11例患者的病灶均局限于皮层或以皮层为主,呈长T1长T2信号,FLAIR及DWI像呈等低信号;病灶以额顶叶最多见;7例病灶形态呈典型的“三角征”;11例患者肿瘤内均见到多发囊变区及等信号分隔;9例瘤周无水肿,无占位效应;增强扫描2例有强化。结论大部分DNT其MRI表现具有特征性,表现为皮层内三角形长T1长T2信号,内有等信号分隔,无占位效应,多数不强化。当病变缺乏特征性表现时,诊断较为困难;特殊胶质-神经原成分是DNT的组织病理学特征。
Objective To investigate the MRI features and pathological features of embryonic dysplastic neuroepithelioma (DNT). Methods MRI data of 11 cases of embryonic dysplastic neuroepithelioma proved by operation and pathology were retrospectively analyzed and compared with low grade astrocytoma, oligodendroglioma, ganglioneuroblastoma, arachnoid cyst Identification, focusing on the occurrence of DNT site, morphological characteristics, MRI signal characteristics, ways to strengthen and so on. Results The lesions of 11 patients were mainly localized in the cortex or the cortex, showing long T1 long T2 signals and low signals of FLAIR and DWI. The lesions were mostly seen with the frontal parietal lobes. The lesions of 7 cases showed a typical triangular shape In 11 cases, multiple cystic areas and isoelectric signs were seen in the tumors. There were no edema in 9 cases and no mass effect in 2 cases. Conclusions Most of the DNTs have MRI features which are characterized by long, long, long T2 signals in the cortex, with equal signal separation and no space-occupying effect, most of which are not intensified. Diagnosis is more difficult when the lesion lacks a characteristic appearance; the special glial-neurogenic component is a histopathological feature of DNT.