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目的探讨变应原皮肤点刺试验与血清免疫球蛋白E(Ig E)检测在小儿哮喘中的诊断价值。方法选取玉林市第一人民医院2015年9月—2016年9月收治的哮喘缓解期患儿46例作为观察组,另选择同期于本院接受体检的健康儿童28例作为对照组。两组受试者行变应原皮肤点刺试验、血清Ig E测定,比较两组受试者5种变应原皮肤点刺试验结果及血清Ig E水平。结果观察组患者变应原阳性率高于对照组(P<0.05)。观察组患儿尘螨、狗毛、花粉、牛奶、香烟变应原皮肤点刺试验阳性率高于对照组(P<0.05)。观察组患儿血清总Ig E高于对照组(P<0.05)。结论变应原皮肤点刺试验安全可靠,可快速筛查和寻找变应原,在小儿哮喘诊断中更具优势,联合血清Ig E检测可提高诊断准确率,为小儿哮喘提供更可靠的诊治依据。
Objective To investigate the diagnostic value of allergen skin prick test and serum immunoglobulin E (Ig E) detection in pediatric asthma. Methods Forty-six children with asthma remission who were admitted to Yulin First People’s Hospital from September 2015 to September 2016 were selected as the observation group. Another 28 healthy children undergoing physical examination during the same period were selected as the control group. Two groups of subjects were allergen skin prick test, serum Ig E determination of two groups of subjects five allergens skin prick test results and serum Ig E levels. Results The positive rate of allergen in observation group was higher than that in control group (P <0.05). The positive rate of skin prick test in dust mites, dog hair, pollens, milk and cigarette allergens in the observation group was higher than that in the control group (P <0.05). The serum IgE in observation group was higher than that in control group (P <0.05). Conclusion The allergen skin prick test is safe and reliable, which can rapidly screen and look for allergens. It is more advantageous in the diagnosis of pediatric asthma. Combined with serum Ig E test can improve the diagnostic accuracy and provide more reliable diagnosis and treatment basis for pediatric asthma .